Wednesday, May 9, 2018
Are common diseases generally caused by 'common' variants?
T he funding mantra of genomewide mapping is that common variants cause common disease (CV-CD). This was convenient for HapMap and other as...
Sunday, May 6, 2018
"All of us" Who are 'us'?
S o the slogan du jour, All Of Us , is the name of a 1.4 billion dollar initiative being launched today by NIH Director Francis Collins. Th...
Thursday, April 26, 2018
Gene mapping: More Monty Python than Monty Python
The gene for ...... (Monty Python) H ere's a link to a famous John Cleese (of Monty Python fame) sketch on gene mapping. We ask y...
Wednesday, April 25, 2018
Improving access to healthcare can usually make malaria go away
Drug resistant malaria has emerged in Southeast Asia several times in history and subsequently spread globally. When there are no other anti...
Tuesday, April 24, 2018
Throw 'em down the stairs! (making grant review fair)
W hen I was active in the grant process, including my duty to serve as a panelist for NIH and NSF, I realized that the work overload, and th...
Wednesday, March 14, 2018
Thinking about science upon entering the field. Part II: What are 'probabilities'?
B elow is the second installment in a short series of posts by a current Penn State graduate student in Chemical Ecology, Tristan Cofe...
Wednesday, February 28, 2018
Rare Disease Day and the promises of personalized medicine
O ur daughter Ellen wrote the post that I republish below 3 years ago, and we've reposted it in commemoration of Rare Disease Day, Febru...
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